knockdown mice

knockdown mice in Shirley, NY
45-1 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY 11967
(1 (631) 1) 372-1052

Contacts

Street address:
45-1 Ramsey Road, Shirley, NY 11967, USA

City / suburb:
Shirley

County:
Suffolk

State:
New York

ZIP code:
11967

Phone:
(1 (631) 1) 372-1052 (Primary Phone)

GPS Longitude:
-72.8805770874023

GPS Latitude:
40.8444747924805

Business description

Creative Animodel's proprietary RNAi technology enables you to induce and reverse ubiquitous gene knockdown in mice at selected points in time! Please

RNA interference has become a widely used approach to perform gene knockdown experiments in cell cultures and more recently transgenic animals. It has developed into a routine method to assess gene function in a fast and easy manner. Since 2008, Creative Animodel's scientists have generated more than 200 RNAi models for innovative biomedical researchers. These RNAi models allow researchers to induce and reverse gene knockdown in transgenic mice at selected time points in vivo.We have developed RNAi-mediated gene knockdown mice by:Silencing lentiviral vectors and adenoviral vectorsTransgenic mice can be generated rapidly by transduction of early embryos with lentiviral silencing vectors and adenoviral vectors, resulting in mice with down regulated target genes. These methodologies offer the possibility of large-scale generation of knockdown transgenic mice for functional genomic studies and enable the production of transgenic mice in 7 weeks.Cre/loxP system as an activate RNAi in a time- and tissue-dependent mannerSingle-copy RNAi constructs are placed into the Rosa26 locus of ES cells by recombinase-mediated cassette exchange and transmitted through the germline of chimaeric mice. The site-specific insertion of single-copy shRNA vectors allows the expedite and reproducible production of knockdown mice and provides an easy and fast approach to assess gene function in vivo.

General information

Business data
City / suburb: Shirley, NY
County: Suffolk
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More details about this business

According to our records, this business is located at 45-1 Ramsey Road, Shirley, NY 11967, USA in Shirley (in Suffolk County), New York 11967, the location GPS coordinates are: 40.8444747924805 (latitude), -72.8805770874023 (longitude). knockdown mice is categorized under Biotechnology Products and Services. You can contact the company by phone at (1 (631) 1) 372-1052.
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